Blood tests

Lab test glossary

Reference ranges, abnormal flags, panels, screening, confirmatory tests, NAAT, PCR, antibodies, variants, and trends.

MedlinePlus + FDA
Lab result interpretation checklist

What to check before reacting to a result: specimen, units, reference range, flags, trends, preparation, and follow-up.

MedlinePlus + FDA
Abnormal lab result next steps

How to think through abnormal, positive, negative, borderline, inconclusive, or conflicting results before acting.

MedlinePlus + CDC
Lab test accuracy, false positives, and false negatives

How to judge analytical validity, clinical validity, specimen limits, timing, confirmatory testing, and overbroad claims.

FDA + MedlinePlus
CLIA-certified lab vs FDA-authorized test

What CLIA lab quality, FDA review, home-use tests, lab-developed tests, and intended-use claims do and do not prove.

CDC + FDA
Lab test privacy, insurance, and data sharing

HIPAA limits, insurance EOBs, cash pay, health apps, DNA data, microbiome samples, research sharing, and deletion questions.

HHS + FTC
Lab test cost, insurance, and cash pay

Preventive vs diagnostic billing, in-network labs, EOBs, cash-pay prices, price transparency, and surprise-bill questions.

CMS + HealthCare.gov
Routine blood tests for preventive health and optimization

CBC, CMP, A1C, lipids, thyroid, iron, vitamins, STI labs, and how to avoid overtesting.

MedlinePlus + USPSTF
Doctor-ordered vs direct-access vs at-home lab tests

How to choose safely by test question, specimen, CLIA lab quality, FDA review, follow-up, privacy, and cost.

FDA + CDC
CBC blood test guide

Red cells, white cells, platelets, hemoglobin, hematocrit, MCV, differential, trends, and follow-up questions.

MedlinePlus + NIDDK + Genetics
Reticulocyte count test

Anemia workups, bone marrow response, blood loss, hemolysis, corrected counts, and CBC context.

MedlinePlus
Peripheral blood smear test

Blood film review, red and white cell morphology, platelets, anemia, and CBC follow-up.

MedlinePlus
Troponin blood test

Heart muscle injury, chest pain evaluation, serial testing, ECG context, and high-sensitivity results.

MedlinePlus
BNP and NT-proBNP heart failure tests

Natriuretic peptides, shortness of breath, swelling, rule-out use, high results, kidney function, obesity, age, AFib, echocardiogram, and urgent symptoms.

MedlinePlus + AHA
ESR blood test

Erythrocyte sedimentation rate, inflammation context, CRP comparison, nonspecific results, and trend questions.

MedlinePlus
LDH isoenzymes test

LDH-1 through LDH-5, tissue-localization limits, hemolysis caveats, and more specific follow-up tests.

MedlinePlus + CDC
D-dimer blood test

Blood-clot rule-out use, DVT and pulmonary embolism context, pretest probability, false positives, age-adjusted cutoffs, imaging, and urgent symptoms.

MedlinePlus + CDC
PT/INR blood test

Prothrombin time, INR, warfarin monitoring, liver context, vitamin K, bleeding, and clotting questions.

MedlinePlus
aPTT blood test

Partial thromboplastin time, heparin monitoring, bleeding workups, clotting factors, and PT/INR comparison.

MedlinePlus
Fibrinogen blood test

Clotting factor I, bleeding workups, DIC, liver context, inflammation, PT/aPTT, and follow-up questions.

MedlinePlus + NCBI
Coagulation factor assays

Factor VIII, IX, XI, fibrinogen, hemophilia, PT/aPTT patterns, bleeding workups, and result limits.

MedlinePlus + NCBI
von Willebrand factor testing

VWD, VWF antigen and activity, factor VIII, mucosal bleeding, platelet adhesion, and repeat testing.

CDC + MedlinePlus
Platelet function testing

Platelet aggregation, closure time, medication effects, inherited platelet defects, VWD context, and specimen limits.

MedlinePlus + CDC + NHLBI
Mixing study blood test

Prolonged PT or aPTT, factor deficiency, inhibitors, incubation patterns, and follow-up testing.

MedlinePlus + NHLBI + CDC
Lupus anticoagulant testing

APS, dRVVT, aPTT-based tests, clot risk, pregnancy loss, anticoagulant interference, and repeat testing.

MedlinePlus + ARUP + CDC
Factor VIII inhibitor testing

Acquired hemophilia, Bethesda assay, factor VIII activity, prolonged aPTT, and urgent bleeding follow-up.

CDC + MedlinePlus + ARUP
Thrombin time and reptilase time testing

Heparin effect, fibrinogen deficiency, dysfibrinogenemia, clot formation, prolonged results, and follow-up tests.

MedlinePlus + Mayo + Labcorp
Factor XIII activity testing

Rare bleeding, normal PT and aPTT, clot stabilization, wound healing, and FXIII deficiency.

MedlinePlus + Mayo + NHLBI
Plasminogen activity testing

PLG deficiency, fibrin breakdown, ligneous conjunctivitis, activity versus antigen, and acquired low results.

MedlinePlus Genetics + Mayo + ARUP
Euglobulin clot lysis time testing

Fibrinolysis, hyperfibrinolysis, unexplained bleeding, PAI-1 context, and clot breakdown.

UW + MedlinePlus + PMC
Alpha-2 antiplasmin activity testing

SERPINF2, activity versus antigen, delayed bleeding, fibrinolysis, and clot breakdown.

Mayo + ARUP + Labcorp
PAI-1 activity testing

SERPINE1, activity versus antigen, delayed bleeding, fibrinolysis, and clot breakdown.

GeneReviews + ARUP + Mayo
Thromboelastography and ROTEM testing

Whole-blood clot initiation, clot strength, fibrinolysis, trauma, surgery, bleeding, and transfusion decisions.

NCBI + PMC
High platelet count interpretation

Thrombocytosis, CBC trends, iron deficiency, inflammation, clot questions, and repeat testing.

MedlinePlus + NHLBI
Low platelet count interpretation

Thrombocytopenia, CBC context, clumping, medicines, bleeding symptoms, and follow-up.

MedlinePlus + NHLBI
High white blood cell count interpretation

Leukocytosis, CBC differential, infection, inflammation, stress, medicines, and follow-up.

MedlinePlus + NCBI
Low white blood cell count interpretation

Leukopenia, neutropenia, CBC differential, infection risk, medicines, and follow-up.

MedlinePlus + NCBI
High neutrophil count interpretation

Neutrophilia, CBC differential, infection, steroids, stress, inflammation, and smear follow-up.

MedlinePlus + NCBI
Low neutrophil count interpretation

Neutropenia, ANC, infection risk, medicines, viral illness, autoimmune disease, and follow-up.

MedlinePlus + NCBI
High lymphocyte count interpretation

Lymphocytosis, CBC differential, viral illness, chronic patterns, smear review, and follow-up.

MedlinePlus + NCBI
Low lymphocyte count interpretation

Lymphocytopenia, immune context, medicines, infections, trends, and when to ask about follow-up.

MedlinePlus + NCBI
High monocyte count interpretation

Monocytosis, absolute count, CBC differential, persistence, infection, inflammation, and follow-up.

MedlinePlus + NHLBI
Low monocyte count interpretation

Monocytopenia, absolute count, CBC context, medicines, immune suppression, persistence, and follow-up.

MedlinePlus + NHLBI + NCBI
High eosinophil count interpretation

Eosinophilia, absolute count, allergies, asthma, parasites, drug reactions, autoimmune disease, and follow-up.

MedlinePlus + CDC + NCBI
Low eosinophil count interpretation

Eosinopenia, absolute count, CBC differential context, steroids, acute stress, cortisol, alcohol intoxication, and trends.

MedlinePlus + NCBI
High basophil count interpretation

Basophilia, CBC differential, allergies, inflammation, thyroid context, MPNs, and follow-up.

MedlinePlus + NCBI
Low basophil count interpretation

Basopenia, CBC context, acute infection, steroid medicines, hyperthyroid context, and trends.

MedlinePlus + NCBI
High immature granulocytes interpretation

Left shift, infection, inflammation, stress response, pregnancy, medications, WBC and ANC context, smear clues, and follow-up.

MedlinePlus + NCBI + CAP/ASH
High band neutrophils interpretation

Bandemia, left shift, immature granulocytes, infection, inflammation, sepsis context, WBC and ANC trends, toxic changes, and follow-up.

MedlinePlus + NCBI + CAP/ASH
High atypical lymphocytes interpretation

Reactive lymphocytes, viral illness, lymphocytosis, smear context, persistence, abnormal cells, and follow-up.

MedlinePlus + NCBI
Blasts on CBC interpretation

Peripheral smear review, immature cells, acute leukemia workup, flow cytometry, bone marrow testing, and urgent follow-up.

NCBI
NRBC present on CBC interpretation

Nucleated red blood cells, peripheral smear review, anemia, hypoxia, marrow stress, newborn context, leukoerythroblastic patterns, and follow-up.

NCBI + MedlinePlus + PMC
Smudge cells on CBC interpretation

Peripheral smear, lymphocytosis, CLL workup, fragile lymphocytes, artifacts, flow cytometry, and follow-up.

NCBI + NCI
Teardrop cells on blood smear interpretation

Dacrocytes, smear artifact, myelofibrosis, marrow infiltration, anemia, leukoerythroblastic patterns, and follow-up.

MedlinePlus + NCBI
Rouleaux on blood smear interpretation

Stacked red cells, inflammation, high protein states, ESR, SPEP, immunofixation, myeloma clues, and follow-up.

MedlinePlus + NCBI
Schistocytes on blood smear interpretation

Fragmented red cells, hemolysis labs, thrombotic microangiopathy, DIC, urgent context, and follow-up.

MedlinePlus + NHLBI + ICSH
Spherocytes on blood smear interpretation

Hereditary spherocytosis, immune hemolysis, bilirubin, reticulocytes, DAT, and follow-up.

MedlinePlus + NCBI + NHLBI
Elliptocytes on blood smear interpretation

Ovalocytes, iron deficiency, thalassemia, hereditary elliptocytosis, anemia patterns, and follow-up.

MedlinePlus + NCBI + PMC
Target cells on blood smear interpretation

Codocytes, liver disease, thalassemia, iron deficiency, hemoglobin disorders, spleen context, and follow-up.

MedlinePlus + NCBI
Burr cells on blood smear interpretation

Echinocytes, artifact, kidney failure, pyruvate kinase deficiency, and follow-up.

NCBI + MedlinePlus
Acanthocytes on blood smear interpretation

Spur cells, liver disease, spleen history, lipids, artifact, and follow-up questions.

NCBI
Stomatocytes on blood smear interpretation

Mouth-shaped red cells, artifact, liver disease, alcohol, hemolysis clues, and follow-up.

MedlinePlus + NCBI + PMC
Bite cells on blood smear interpretation

Degmacytes, G6PD, oxidative hemolysis, Heinz bodies, medicines, and urgent clues.

NCBI + MedlinePlus
Howell-Jolly bodies on blood smear interpretation

Spleen filtering, hyposplenia, asplenia, sickle cell context, B12/folate clues, and follow-up.

NCBI + MedlinePlus
Basophilic stippling on blood smear interpretation

Coarse vs fine stippling, lead exposure, thalassemia, sideroblastic anemia, and CBC context.

NCBI + MedlinePlus + CDC
Pappenheimer bodies on blood smear interpretation

Iron granules, Prussian blue stain, sideroblastic anemia, thalassemia, asplenia, lead, and follow-up.

NCBI + MedlinePlus
Hypersegmented neutrophils on blood smear interpretation

B12, folate, macrocytosis, megaloblastic anemia, medication context, and follow-up questions.

NCBI + MedlinePlus
Cabot rings on blood smear interpretation

Ring-shaped inclusions, megaloblastic anemia clues, B12/folate context, and follow-up.

NCBI + MedlinePlus
Toxic granulation on blood smear interpretation

Neutrophil toxic changes, Dohle bodies, vacuoles, infection, inflammation, left shift, sepsis context, G-CSF, chemotherapy recovery, and urgent clues.

MedlinePlus + NCBI
Dysplastic neutrophils on blood smear interpretation

Pseudo-Pelger cells, hypogranulation, MDS clues, medication effects, and follow-up.

NCBI + NCI
Left shift on blood smear interpretation

Bands, immature granulocytes, metamyelocytes, myelocytes, infection, inflammation, toxic changes, urgent symptoms, smear review, and follow-up.

MedlinePlus + NCBI + CAP/ASH
Myelocytes on CBC differential interpretation

Left shift, immature granulocytes, infection, inflammation, marrow recovery, medication context, persistent high WBC, smear review, and follow-up.

MedlinePlus + NCBI + CAP/ASH
Metamyelocytes on CBC differential interpretation

Left shift, bands, immature granulocytes, infection, inflammation, pregnancy or treatment context, persistent WBC changes, smear review, and follow-up.

MedlinePlus + NCBI + CAP/ASH
Promyelocytes on CBC differential interpretation

Left shift, blasts, Auer rods, AML and APL risk, coagulation clues, smear review, flow cytometry, and urgent hematology follow-up.

MedlinePlus + NCI + NCBI
Auer rods on blood smear interpretation

AML clues, myeloid blasts, promyelocytes, APL bleeding risk, smear review, flow cytometry, and urgent hematology follow-up.

MedlinePlus + NCI + NCBI
Monoblasts on CBC differential interpretation

Monocyte-lineage blasts, promonocytes, AML clues, smear review, flow cytometry, bone marrow workup, and urgent follow-up.

MedlinePlus + NCI + NCBI
Reactive lymphocytes vs blasts interpretation

CBC wording, smear review, infection context, leukemia questions, and follow-up.

NCBI + MedlinePlus
Promonocytes on CBC differential interpretation

Monocyte-lineage immature cells, blast equivalents, monoblasts, AML clues, smear review, flow cytometry, and urgent follow-up.

MedlinePlus + NCI + NCBI
Abnormal lymphocytes on CBC interpretation

Reactive cells, blasts, analyzer flags, smear review, and follow-up questions.

NCBI + MedlinePlus
Plasma cells on CBC differential interpretation

Smear review, reactive causes, atypical plasma cells, SPEP, immunofixation, serum free light chains, myeloma clues, and follow-up.

MedlinePlus + NCI + NCBI
Immature lymphocytes on CBC interpretation

Analyzer flags, reactive cells, lymphoblasts, blasts, smear review, flow cytometry, urgent symptoms, and follow-up.

MedlinePlus + NCBI + NCI
Leukemoid reaction CBC interpretation

Very high WBC, neutrophilia, left shift, infection, medicine effects, CML questions, and follow-up.

NCBI + Merck
Leukoerythroblastic blood smear interpretation

NRBCs, immature granulocytes, teardrop cells, marrow stress, myelophthisic patterns, newborn context, and follow-up.

NCBI + MedlinePlus + PMC
Creatine kinase CK test

Muscle injury, rhabdomyolysis, exercise effects, medicines, kidney risk, and troponin context.

MedlinePlus
Amylase and lipase blood tests

Pancreatitis context, salivary sources, timing, chronic disease follow-up, and urgent symptoms.

MedlinePlus + NIDDK + Genetics
GGT blood test

Gamma-glutamyl transferase, liver and bile-duct patterns, ALP comparison, alcohol context, and limits.

MedlinePlus
Alkaline phosphatase ALP blood test

ALP patterns, liver and bone sources, GGT comparison, bile-duct questions, and follow-up testing.

MedlinePlus
Bilirubin blood test

Total, direct, and indirect bilirubin, jaundice context, hemolysis, liver panels, and urgent symptoms.

MedlinePlus
ALT blood test

Alanine aminotransferase, liver-cell injury patterns, AST comparison, medicines, and follow-up questions.

MedlinePlus
AST blood test

Aspartate aminotransferase, liver and muscle sources, ALT comparison, CK context, and liver-panel patterns.

MedlinePlus
Hepatitis A, B, and C blood tests

HAV IgM, hepatitis B triple panel, HCV antibody and RNA, exposure timing, and liver enzyme context.

CDC
High ferritin with liver enzymes

Iron overload, inflammation, fatty liver, transferrin saturation, ALT/AST/GGT patterns, and follow-up.

MedlinePlus + NIDDK + NIH ODS
Liver fibrosis blood tests and FIB-4 interpretation

AST, ALT, platelets, age, APRI, elastography, fatty liver risk, and follow-up questions.

NIDDK + AASLD + MedlinePlus
Hepatitis B surface antibody after vaccination

Anti-HBs, vaccine response, waning antibodies, triple panel context, and retesting questions.

CDC
AFP blood test

Alpha-fetoprotein, pregnancy screening, liver cancer surveillance context, tumor marker limits, and follow-up questions.

MedlinePlus + NCI
Ceruloplasmin blood test

Copper transport, Wilson disease workups, copper deficiency, urine copper, and liver or neurologic clues.

MedlinePlus
Basic metabolic panel

Glucose, calcium, sodium, potassium, chloride, CO2/bicarbonate, BUN, creatinine, fasting, kidney context, and BMP versus CMP.

MedlinePlus + NIDDK + Genetics
Comprehensive metabolic panel

Glucose, electrolytes, kidney markers, liver markers, proteins, calcium, fasting, and BMP comparison.

MedlinePlus + NIDDK + Genetics
A1C blood test guide

HbA1c ranges, fasting, repeat testing, red-blood-cell limits, and diabetes follow-up.

CDC + NIDDK
Lipid panel guide

LDL, HDL, triglycerides, total cholesterol, non-HDL, fasting, calculated LDL, ApoB/Lp(a), and risk context.

CDC + NIH
ApoB and Lp(a) blood tests

Advanced lipid markers, inherited risk, particle risk, and result caveats.

MedlinePlus + AHA
Fasting insulin test

Insulin resistance, glucose and A1C context, fasting prep, and limits for optimization use.

MedlinePlus + NIDDK + Genetics
Cortisol blood test

Blood, saliva, and urine cortisol testing, timing, Cushing syndrome, adrenal insufficiency, and follow-up.

MedlinePlus + NIDDK + Genetics
Cortisol saliva vs blood test

Late-night saliva, morning blood, 24-hour urine, timing, Cushing, adrenal questions, and collection limits.

MedlinePlus
Testosterone levels test

Total and free testosterone, morning timing, symptoms, repeat testing, and hormone context.

MedlinePlus
Estradiol and progesterone tests

Cycle timing, fertility, menopause, hormone therapy monitoring, and why one snapshot can mislead.

MedlinePlus + FDA
FSH and LH tests

Fertility workups, menopause, puberty, pituitary questions, cycle timing, and hormone context.

MedlinePlus
DHEA-S test

Adrenal androgens, PCOS, CAH, high-androgen symptoms, supplement caveats, and follow-up.

MedlinePlus + NICHD
Prolactin blood test

High prolactin, irregular periods, nipple discharge, fertility, thyroid and kidney causes, medications, repeat testing, and MRI follow-up.

MedlinePlus + NIDDK + Genetics
AMH test

Ovarian reserve, fertility treatment planning, PCOS context, DTC claims, and fertility prediction limits.

MedlinePlus + ACOG + ASRM + NICHD
Calcium blood test

Total calcium, corrected calcium, ionized calcium, albumin, PTH, vitamin D, kidney context, medicines, supplements, and follow-up.

MedlinePlus + NKF
Magnesium blood test

Serum magnesium, low or high results, kidney function, medications, supplements, and RBC magnesium claims.

MedlinePlus + NIH ODS + NIDDK
Phosphorus blood test

Phosphate, high or low phosphorus, kidney disease, calcium, PTH, vitamin D, magnesium, diet, supplements, and follow-up.

MedlinePlus + NKF
Parathyroid hormone PTH test

Calcium patterns, phosphorus, vitamin D, magnesium, kidney disease, hyperparathyroidism, and follow-up.

MedlinePlus + NIDDK + NIH ODS
Urinalysis test

Dipstick, microscopy, leukocyte esterase, nitrites, blood, protein, glucose, ketones, UTI clues, kidney follow-up, and sample quality.

MedlinePlus + CDC
Urine albumin-to-creatinine ratio (UACR)

Albuminuria, kidney disease risk, diabetes, blood pressure, repeat testing, and eGFR context.

MedlinePlus + NIDDK + CDC
Urine culture test

UTI bacteria, clean-catch samples, colony growth, antibiotic susceptibility, contamination, and follow-up.

MedlinePlus + CDC
Electrolyte panel blood test

Sodium, potassium, chloride, CO2/bicarbonate, anion gap, dehydration, kidney function, medicines, urgent symptoms, and follow-up.

MedlinePlus + NKF
Albumin blood test

Liver-made blood protein, low or high results, kidney protein loss, nutrition, dehydration, and CMP context.

MedlinePlus
Sodium and potassium blood test results

Electrolyte safety, high or low sodium and potassium, kidney function, medications, symptoms, and repeat testing.

MedlinePlus
Total protein, globulin, and A/G ratio interpretation

Total protein, albumin, globulin, immune proteins, liver, kidney, inflammation, dehydration, and CMP patterns.

MedlinePlus
Serum protein electrophoresis (SPEP)

Protein fractions, M-spike, MGUS, free light chains, immunofixation, myeloma clues, and follow-up.

MedlinePlus + NCI
Anion gap blood test

Electrolyte calculations, CO2/bicarbonate, acid-base balance, high or low anion gap, and urgent context.

MedlinePlus
Chloride and CO2/bicarbonate blood test

Electrolyte panel patterns, acid-base balance, dehydration, vomiting, diarrhea, medicines, and anion gap context.

MedlinePlus + NCBI
BUN/creatinine ratio

BUN, creatinine, eGFR, kidney function, dehydration, protein intake, low muscle mass, and trend context.

MedlinePlus + NIDDK + NCBI
Cystatin C kidney function test

eGFR confirmation, creatinine comparison, CKD risk, low muscle mass, and result limits.

NIDDK + NKF
Urine protein-to-creatinine ratio

UPCR, total urine protein, UACR comparison, 24-hour urine context, and kidney follow-up.

MedlinePlus + NIDDK + NKF
LDH, haptoglobin, and hemolysis labs

Hemolytic anemia patterns, red-cell destruction, reticulocytes, bilirubin, smear review, and sample caveats.

MedlinePlus
Blood test reference ranges

Normal ranges, high and low flags, units, trends, lab-to-lab differences, critical values, and context.

MedlinePlus + FDA
Fasting for blood tests

8-12 hour fasting, water, coffee, gum, medicines, supplements, diabetes safety, glucose, lipids, and accidental eating.

MedlinePlus + CDC
TSH thyroid blood test

High and low TSH, free T4, T3, thyroid antibodies, biotin interference, screening limits, symptoms, and follow-up questions.

MedlinePlus + NIDDK + Genetics
Ferritin and iron studies

Ferritin, serum iron, TIBC/transferrin, transferrin saturation, CBC context, inflammation, iron deficiency, and iron overload.

MedlinePlus + NHLBI
Vitamin D blood test

25(OH)D, active vitamin D, deficiency risk, toxicity, supplements, calcium, kidney/PTH context, and screening limits.

MedlinePlus + NIH
Vitamin B12 and folate test

Deficiency, anemia, CBC context, homocysteine, and supplement caveats.

MedlinePlus
Homocysteine and methylmalonic acid tests

B12, folate, MMA, kidney effects, cardiovascular claims, and follow-up questions.

MedlinePlus + NIH ODS
CRP and hs-CRP blood test

Standard CRP versus hs-CRP, inflammation causes, heart-risk use, result limits, repeat testing, and follow-up questions.

MedlinePlus + AHA
Liver function tests

ALT, AST, ALP, GGT, bilirubin, albumin, PT/INR, prep, and result limits.

MedlinePlus
Kidney function tests

eGFR, creatinine, BUN, UACR, kidney-risk context, preparation, and result caveats.

MedlinePlus + NIDDK + Genetics

STI and STD testing

STI testing guide

When to test, what tests cover, self-collection, and follow-up questions.

CDC
STI symptoms vs routine screening

When testing is diagnostic, which symptoms need clinic evaluation, and why a routine panel may not be enough.

CDC
STI symptoms but negative results

Why negative results can still miss timing, body sites, panel gaps, herpes lesions, UTI, BV, yeast, or Mgen.

CDC
STI testing for sores, ulcers, or rash

Lesion swabs, HSV testing, syphilis blood tests, HIV testing, monkeypox rash testing, and follow-up questions.

CDC
STI testing for discharge

Urethral, vaginal, cervical, and rectal discharge testing, including STI, BV, yeast, UTI, and Mgen overlap.

CDC
STI testing for pelvic or testicular pain

PID, epididymitis, torsion red flags, UTI overlap, pregnancy questions, and when pain needs urgent care.

CDC
STI testing after condom break or exposure

PEP within 72 hours, emergency contraception, baseline tests, window periods, body-site swabs, and repeat testing.

CDC
STI testing after sexual assault

SAFE exams, baseline STI testing, HIV PEP timing, emergency contraception, vaccines, privacy, and follow-up.

CDC + DOJ
STI testing after an anonymous partner

One-night stand timing, baseline tests, HIV PEP, emergency contraception, body-site swabs, and repeat testing.

CDC
STI testing after vacation or travel sex

Travel partner timing, PEP, emergency contraception, body-site swabs, vaccines, records, and repeat testing.

CDC Yellow Book
STI testing before stopping condoms

Recent results, window periods, body-site testing, HIV prevention, pregnancy prevention, and partner agreements.

CDC
STI testing in open relationships

Recurring testing, multiple partners, body-site swabs, PrEP, DoxyPEP, vaccines, privacy, and result-sharing agreements.

CDC
STI testing after sharing sex toys

Shared toy timing, condoms on toys, cleaning, body-site swabs, BV, HPV, HIV anxiety, and repeat testing.

CDC
STI testing after genital touching or fingering

Hand jobs, mutual masturbation, HIV anxiety, skin-to-skin STIs, symptoms, sores, and when testing matters.

CDC
STI testing after dry humping or genital rubbing

Clothing, grinding, skin-to-skin STIs, HIV anxiety, pregnancy questions, symptoms, and when testing matters.

CDC
STI testing after precum exposure

Pre-ejaculate, HIV risk, pregnancy questions, PEP, emergency contraception, body sites, symptoms, and timing.

CDC + NIH
STI testing after sex without ejaculation

Pulling out, body sites, HIV PEP, pregnancy prevention, symptoms, condoms, and repeat testing.

CDC
STI testing after ejaculation outside the body

Semen on skin, vulva, clothing, surfaces, pregnancy questions, HIV risk, PEP, symptoms, and timing.

CDC
STI testing after oral sex

Throat swabs, urine limits, syphilis and HIV blood tests, oral-anal exposure, symptoms, and timing questions.

CDC
STI testing after anal sex

Rectal swabs, urine limits, HIV PEP and PrEP timing, proctitis symptoms, blood tests, and follow-up questions.

CDC
STI testing after a partner has an STI

Known exposure steps, when testing is not enough, EPT, HIV PEP timing, body-site swabs, and repeat testing.

CDC
HIV testing window period

Test types, timing after exposure, negative results, and follow-up testing.

CDC
Chlamydia and gonorrhea testing

Screening, urine and swab samples, throat and rectal testing, and follow-up.

CDC
Syphilis testing guide

RPR, VDRL, treponemal tests, screening, pregnancy, and follow-up.

CDC
Herpes testing guide

HSV swabs, blood tests, false positives, and why routine screening is different.

CDC + USPSTF
At-home STI tests vs clinic testing

Self-tests, self-collection, FDA authorization, body-site coverage, and follow-up.

CDC + FDA
Positive STI result next steps

Treatment, partner notification, confirmatory testing, prevention, and retesting.

CDC
STI retesting after treatment

3-month retesting, test-of-cure situations, syphilis follow-up titers, and when symptoms need care.

CDC
Partner notification and EPT

Partner notification, expedited partner therapy, chlamydia and gonorrhea partner treatment, and testing caveats.

CDC
Free and low-cost STI testing

CDC GetTested, health departments, Title X clinics, insurance, privacy, and follow-up.

CDC + HHS
STI testing privacy and insurance

EOBs, confidential communications, preventive coverage, Title X, cash pay, and portal privacy questions.

CDC + HHS
Full STI panel

What panels include, what they miss, body-site testing, herpes, timing, and follow-up.

CDC
STI testing after a new partner

What to test for, when to test, body-site swabs, symptoms, and repeat testing.

CDC
STI testing for pregnancy planning

Before pregnancy, first prenatal screening, partner testing, and repeat testing questions.

CDC
DoxyPEP and STI testing

Who should discuss doxyPEP, what follow-up testing is still needed, and what it does not cover.

CDC
PrEP labs and STI testing follow-up

HIV testing, kidney function, hepatitis B, lipids, STI screening, and oral versus injectable follow-up schedules.

CDC + USPSTF
PrEP vs PEP testing timelines

72-hour PEP window, baseline HIV tests, follow-up HIV testing, STI screening, and when PrEP monitoring begins.

CDC
Extragenital STI testing

Throat and rectal swabs, urine-test limits, site-of-contact testing, and follow-up questions.

CDC
Hepatitis B and C testing

HBV triple panel, HCV antibody and RNA testing, vaccines, pregnancy, and STI-panel caveats.

CDC
Trichomoniasis testing

Why trich may be missing from panels, NAATs, wet mount limits, symptoms, and retesting.

CDC
HPV testing and Pap tests

Cervical cancer screening, cotesting, self-collection, abnormal results, and STI-panel limits.

CDC + NCI
Mycoplasma genitalium testing

When Mgen testing is considered, NAAT samples, resistance, persistent symptoms, and panel limits.

CDC + FDA
BV and yeast testing vs STI testing

Vaginitis swabs, pH, wet mount, NAAT panels, symptoms, and STI testing gaps.

CDC + FDA
UTI testing vs STI testing

Urinalysis, urine culture, STI urine NAATs, symptoms, and when both may be needed.

CDC + NIH
Pelvic exam vs STI testing

Pelvic exams, Pap and HPV tests, STI swabs, urine tests, blood tests, and what to ask.

CDC + NCI

Genetics and microbiome

Direct-to-consumer genetic testing

DNA health reports, clinical confirmation, privacy, and GINA limits.

FDA + NIH
When to use a genetic counselor

Family history, DTC DNA results, clinical confirmation, pregnancy planning, and family risk.

CDC + NIH
Pharmacogenomics testing

Medication-response genes, FDA labeling, CPIC guidance, and when to ask about blood, saliva, or buccal samples.

NIH + MedlinePlus + GeneReviews + NCI
Carrier screening genetic test

Pregnancy planning, recessive risk, partner testing, expanded panels, and residual risk.

ACOG + CDC
Raw DNA upload privacy risks

Third-party reports, genetic data sharing, clinical confirmation, family implications, and GINA limits.

FDA + FTC
FDA-authorized genetic tests

What authorization means, claim boundaries, carrier reports, genetic health risk, and confirmation limits.

FDA
Polygenic risk score interpretation

PRS risk estimates, ancestry validation, family history, clinical action limits, and counseling questions.

NHGRI + FDA
Whole genome sequencing reports

WGS vs WES, VUS, secondary findings, reanalysis, family implications, and privacy questions.

MedlinePlus + CDC + NHGRI
Hereditary cancer genetic testing

BRCA, Lynch syndrome, family history, tumor testing, VUS, counseling, and family testing.

NCI + CDC + USPSTF
Tumor genomic vs inherited genetic testing

Somatic, germline, biomarker testing, cancer treatment decisions, family risk, and confirmation.

NCI + CDC + MedlinePlus
Inherited heart disease genetic testing

Family history, familial hypercholesterolemia, cardiomyopathy, arrhythmia syndromes, VUS, and cascade testing.

CDC + MedlinePlus Genetics + AHA
Newborn screening vs genetic testing

Heel-stick blood spots, hearing, heart screening, state panels, positive screens, and confirmatory testing.

NIH + CDC
MTHFR testing claims

Common variants, folate, folic acid, homocysteine, pregnancy claims, rare disease context, and report limits.

CDC + MedlinePlus
Prenatal screening vs diagnostic genetic testing

NIPT/cfDNA, serum screening, ultrasound, CVS, amniocentesis, positive screens, and counseling.

ACOG + CDC
HLA-B27 test

Spondyloarthritis, ankylosing spondylitis, reactive arthritis, uveitis, inflammatory back pain, and what positive or negative results can mean.

MedlinePlus + NIAMS
Celiac HLA typing

DQ2, DQ8, genetic susceptibility, ruling out celiac disease, blood tests, gluten intake, and biopsy context.

NIDDK + MedlinePlus + ACG
APOE genetic testing claims

Alzheimer's risk, e4, lipid disorders, direct-to-consumer reports, counseling, and limits.

MedlinePlus + FDA + NIA
CYP2C19 pharmacogenetic test

Clopidogrel, PPIs, antidepressants, poor and rapid metabolizers, FDA labels, CPIC guidance, and limits.

MedlinePlus + CPIC + FDA
BRCA testing vs broad cancer panels

BRCA1/BRCA2, hereditary cancer panels, VUS results, counseling, and broad-panel tradeoffs.

NCI + CDC
BRCA VUS result interpretation

Variant uncertainty, family-history context, reclassification, and when a VUS should or should not change care.

NCI + MedlinePlus + NHGRI + CDC
PALB2 genetic testing result interpretation

Breast cancer risk, pancreatic and ovarian risk questions, VUS results, tumor-only findings, and family testing.

NCI + CDC
CHEK2 genetic testing result interpretation

Breast cancer risk, colon and prostate risk questions, VUS results, tumor-only findings, and family testing.

GeneReviews + NCI
ATM genetic testing result interpretation

Breast cancer risk, pancreatic and prostate risk questions, VUS results, tumor-only findings, radiation questions, and family testing.

MedlinePlus + NCI
BARD1 genetic testing result interpretation

Breast cancer risk, ovarian-risk questions, VUS results, tumor-only findings, and family testing.

NCI + CDC
RAD51C and RAD51D genetic testing result interpretation

Ovarian cancer risk, breast-risk questions, VUS results, tumor-only findings, and family testing.

NCI + CDC
BRIP1 genetic testing result interpretation

Ovarian cancer risk, breast-risk questions, VUS results, tumor-only findings, and family testing.

NCI + CDC
PTEN hamartoma tumor syndrome genetic testing

Cowden syndrome, cancer-risk context, VUS results, tumor-only findings, and family testing.

GeneReviews + NCI
Lynch syndrome genetic testing

Tumor screening, germline testing, colorectal and endometrial cancer risk, family history, and counseling.

CDC + NCI
Familial hypercholesterolemia genetic testing

FH, high LDL cholesterol, family history, cascade screening, negative results, and treatment context.

CDC + MedlinePlus + AHA
FH clinical criteria vs genetic testing

Familial hypercholesterolemia diagnosis, LDL thresholds, family history, cascade screening, and DNA limits.

CDC + MedlinePlus + AHA
Hereditary hemochromatosis genetic testing

HFE variants, iron overload, transferrin saturation, ferritin, family testing, and treatment context.

CDC + MedlinePlus + NIDDK
Alpha-1 antitrypsin deficiency testing

AAT blood levels, SERPINA1 genetic testing, COPD, liver disease, and family testing.

MedlinePlus + NHLBI + GeneReviews
G6PD test: enzyme and genetics

Enzyme activity, inherited hemolysis risk, triggers, newborn jaundice, and genetic-test caveats.

MedlinePlus
Hemoglobin electrophoresis and thalassemia

Hemoglobin types, sickle trait, thalassemia, newborn screening follow-up, carrier screening, and genetic counseling questions.

MedlinePlus + NHLBI
Long QT syndrome genetic testing

ECG context, inherited arrhythmia risk, variant interpretation, medication triggers, and family screening.

NHLBI + MedlinePlus + AHA
Marfan syndrome genetic testing

FBN1, aortic screening, clinical diagnosis, variant uncertainty, and family follow-up.

NHLBI + GeneReviews + MedlinePlus
HHT genetic testing

Hereditary hemorrhagic telangiectasia, ENG, ACVRL1, SMAD4, AVM screening, anemia, and family follow-up.

GeneReviews + MedlinePlus
Ehlers-Danlos genetic testing

hEDS limits, vascular EDS red flags, family screening, and connective-tissue safety questions.

GeneReviews + MedlinePlus + NIAMS
Hereditary thrombophilia testing

Factor V Leiden, prothrombin, protein C/S, antithrombin, family testing, pregnancy planning, and when results change care.

ASH + MedlinePlus
Hereditary cardiomyopathy genetic testing

HCM, DCM, ARVC, family screening, variants, and when imaging still matters.

AHA + GeneReviews + ACC
Hereditary kidney disease genetic testing

Hematuria, proteinuria, Alport clues, kidney biopsy context, hearing and eye findings, and family testing.

GeneReviews + NIDDK
Hereditary arrhythmia panel testing

Long QT, Brugada, CPVT, sudden-death family history, variants, and cardiac genetics counseling.

GeneReviews + MedlinePlus
Familial thoracic aortic aneurysm and dissection genetic testing

Aortic imaging, Marfan and Loeys-Dietz clues, familial TAAD panels, and cascade screening.

GeneReviews + MedlinePlus
APOE testing for Alzheimer risk

Alzheimer risk, APOE e4, family history, memory symptoms, and limits of prediction.

MedlinePlus + FDA + NIA
Hereditary pancreatitis genetic testing

PRSS1, SPINK1, CFTR, CTRC, recurrent pancreatitis, family testing, and counseling questions.

GeneReviews + MedlinePlus
HLA-B27 blood test

Spondyloarthritis, ankylosing spondylitis, reactive arthritis, uveitis, inflammatory back pain, and what positive or negative results can mean.

MedlinePlus + NIAMS
MTHFR genetic testing claims

C677T, A1298C, homocysteine, folate, pregnancy, clot claims, and routine-testing limits.

ACMG + MedlinePlus + NIH
HLA celiac genetic testing

Gluten-free diet caveats, uncertain results, family risk, rule-out use, antibody testing, and biopsy context.

NIDDK + MedlinePlus + ACG
Factor V Leiden testing

F5 variant testing, clot risk, APC resistance, pregnancy, estrogen exposure, and family history.

GeneReviews + MedlinePlus
Prothrombin G20210A testing

F2 mutation, venous clot risk, family history, pregnancy, estrogen exposure, and selective thrombophilia testing.

GeneReviews + MedlinePlus + ASH
Protein C, protein S, and antithrombin testing

Inherited and acquired thrombophilia, timing after thrombosis, anticoagulants, repeat testing, and family risk.

ASH + MedlinePlus + ARUP
Antiphospholipid syndrome antibody testing

Lupus anticoagulant, anticardiolipin, beta-2 glycoprotein I, repeat testing, clot risk, and pregnancy loss.

MedlinePlus + NHLBI
JAK2 testing for unexplained clots

Myeloproliferative neoplasms, high platelets, high hematocrit, unusual-site thrombosis, and CBC clues.

MedlinePlus + ARUP
CALR and MPL testing for MPNs

JAK2 reflex panels, persistent thrombocytosis, ET, PMF, CBC clues, and hematology follow-up.

Mayo + ARUP + MedlinePlus
BCR-ABL1 testing for CML

Philadelphia chromosome, PCR monitoring, CBC and smear clues, FISH, karyotype, and leukemia follow-up.

MedlinePlus + NCI + ARUP
KIT mutation testing for mast cell disorders

Systemic mastocytosis, KIT D816V, tryptase, allergy-like symptoms, bone marrow, and test limits.

NCI + ARUP
PNH flow cytometry testing

Paroxysmal nocturnal hemoglobinuria, hemolysis, unusual clots, CD55/CD59, FLAER, clone size, and monitoring.

MedlinePlus + ARUP + NCBI
DDX41 genetic testing for inherited myeloid risk

MDS, AML, cytopenias, adult-onset inherited risk, germline confirmation, and donor selection.

NCI + GeneReviews
TP53 testing in blood cancer workups

AML, MDS, tumor sequencing, germline risk, Li-Fraumeni syndrome, and family implications.

GeneReviews + MedlinePlus
RUNX1 genetic testing for familial platelet disorder

Inherited platelet dysfunction, bleeding, MDS, AML, germline confirmation, and donor selection.

GeneReviews + NCI
GATA2 deficiency genetic testing

MDS, AML, immunodeficiency, monocytopenia, HPV disease, lymphedema, and family testing.

NCI + NIAID
SAMD9 and SAMD9L testing can clarify inherited marrow failure, monosomy 7, and donor risk

Inherited marrow failure, monosomy 7, germline confirmation, donor selection, and family follow-up.

NCI + GeneReviews + PMC
ETV6 genetic testing for inherited thrombocytopenia

Low platelets, bleeding, leukemia predisposition, germline confirmation, and family testing.

GeneReviews + NCBI
ANKRD26 genetic testing for inherited thrombocytopenia

Low platelets, bleeding, 5' UTR variants, myeloid risk, family testing, and surveillance.

GeneReviews + PMC
MECOM genetic testing for inherited marrow failure

Amegakaryocytic thrombocytopenia, cytopenias, marrow failure, germline confirmation, and donors.

NCI + PMC
RASopathy genetic testing

Noonan spectrum, CFC, Costello, Legius/NF1 overlap, prenatal clues, family testing, and counseling.

GeneReviews + MedlinePlus + NCI
Telomere biology disorder genetic testing

Dyskeratosis congenita, short telomeres, marrow failure, pulmonary fibrosis, and family testing.

GeneReviews + NCI + MedlinePlus
VHL genetic testing

Von Hippel-Lindau syndrome, hemangioblastomas, kidney cancer, pheochromocytoma, and family testing.

GeneReviews + NCI
MEN1 genetic testing

Parathyroid, pituitary, pancreatic NETs, family screening, deletion testing, and VUS.

GeneReviews + NIDDK + MedlinePlus
SDHx paraganglioma and pheochromocytoma genetic testing

SDHA, SDHB, SDHC, SDHD, SDHAF2, tumor location clues, imprinting, metastatic risk, and family testing.

GeneReviews + MedlinePlus + NCI + PMC
RET MEN2 genetic testing

Multiple endocrine neoplasia type 2, medullary thyroid cancer, pheochromocytoma, family testing, and risk-specific follow-up.

GeneReviews + MedlinePlus
NF1 genetic testing for tumor predisposition

Neurofibromatosis type 1, mosaicism, tumor surveillance, variant interpretation, and family testing.

GeneReviews + MedlinePlus + NCI + PMC
TSC1/TSC2 genetic testing

TSC, mosaicism, seizures, skin findings, kidney angiomyolipomas, LAM, variants, and family follow-up.

GeneReviews + MedlinePlus
PTCH1 genetic testing

Gorlin syndrome, jaw cysts, SUFU context, skin cancer risk, VUS results, and family follow-up.

GeneReviews + NCI
BAP1 tumor predisposition genetic testing

Uveal melanoma, mesothelioma, kidney cancer, tumor-only findings, VUS results, and family testing.

GeneReviews + NCI
DICER1 syndrome genetic testing

Pleuropulmonary blastoma, thyroid nodules, ovarian tumors, tumor-only findings, VUS results, and family testing.

GeneReviews + NCI
SMARCA4 genetic testing

Rhabdoid tumor predisposition syndrome type 2, SCCOHT, germline versus tumor results, family testing, and counseling.

GeneReviews + NCI
FH fumarate hydratase tumor predisposition genetic testing

HLRCC, kidney cancer risk, leiomyomas, tumor-only findings, VUS results, and family testing.

GeneReviews + NCI
MAX hereditary paraganglioma genetic testing

Pheochromocytoma, cluster 2, germline confirmation, family testing, and individualized follow-up.

GeneReviews + MedlinePlus
TMEM127 genetic testing

Hereditary PPGL risk, cluster 2 biology, tumor-vs-germline context, metanephrines, surveillance, and family follow-up.

GeneReviews + MedlinePlus + NCI + PMC
EPAS1 paraganglioma genetic testing

HIF2A, pheochromocytoma, polycythemia, somatostatinoma, mosaicism, tumor testing, and family-risk caveats.

GeneReviews + PMC
SDHA paraganglioma genetic testing

Low-penetrance SDHx context, PPGL risk, GIST, incidental findings, family testing, and surveillance.

GeneReviews + MedlinePlus + PMC
VHL vs SDHx paraganglioma genetic testing

VHL multi-organ clues, SDHx paraganglioma patterns, kidney cancer, CNS tumors, family testing, and surveillance.

GeneReviews + PMC
Paraganglioma tumor testing vs germline testing

Somatic vs inherited changes, paired tumor-normal testing, family risk, SDHx, VHL, and counseling.

GeneReviews + PMC
RET vs VHL pheochromocytoma genetic testing

MEN2, kidney cancer clues, hemangioblastomas, thyroid surveillance, family testing, and inherited-risk follow-up.

GeneReviews + PMC
NF1 pheochromocytoma genetic testing

Neurofibromatosis type 1, blood pressure, metanephrines, tumor testing, family risk, and counseling.

GeneReviews + PMC
MEN2A vs MEN2B genetic testing

RET variants, medullary thyroid cancer, pheochromocytoma, parathyroid clues, childhood timing, and family testing.

GeneReviews + NCI
Mosaic NF1 genetic testing

Segmental neurofibromatosis, blood testing limits, tissue testing, tumor findings, family risk, and counseling.

GeneReviews + NIH
RET variant of uncertain significance interpretation

MEN2, medullary thyroid cancer, VUS reports, family testing limits, reclassification, and counseling.

GeneReviews + MedlinePlus + ACMG
Negative RET testing with medullary thyroid cancer

Germline testing, tumor testing, MEN2, sporadic MTC, family risk, and follow-up questions.

NCI + GeneReviews + MedlinePlus
RET tumor testing vs germline testing

Somatic variants, inherited MEN2 risk, paired tumor-normal testing, family follow-up, and counseling.

NCI + GeneReviews + ATA
Medullary thyroid cancer genetic counseling questions

RET test type, exact variant, family cascade testing, calcitonin, pheochromocytoma screening, and follow-up.

NCI + GeneReviews + ATA
MEN2 family variant testing

Known RET variant, true negative vs VUS, cascade testing, children, and family follow-up.

NCI + GeneReviews + ATA
RET prenatal and childhood testing questions

MEN2 timing, childhood risk, family variants, prenatal decisions, and specialist follow-up.

NCI + GeneReviews
Positive RET test next steps

Germline vs tumor RET result, MEN2 next steps, family testing, and counseling.

NCI + GeneReviews + ATA
MEN2 surveillance after positive RET testing

Calcitonin, thyroid planning, pheochromocytoma, parathyroid screening, and family follow-up.

NCI + GeneReviews
RET V804M variant interpretation

MEN2A, familial medullary thyroid cancer, moderate-risk language, family testing, and follow-up.

NCI + GeneReviews
RET codon 918 MEN2B questions

M918T, medullary thyroid cancer risk, childhood timing, tumor versus germline testing, and family follow-up.

NCI + GeneReviews
RET codon 634 MEN2A questions

C634 variants, medullary thyroid cancer, pheochromocytoma, parathyroid context, and family testing.

NCI + GeneReviews
RET risk category interpretation

MEN2, ATA-style risk language, exact variant, germline versus tumor testing, and specialist follow-up.

NCI + GeneReviews
RET codon 609, 611, 618, and 620 questions

MEN2A, familial medullary thyroid cancer, exact variant, risk category, and family testing.

NCI + GeneReviews
RET negative family variant testing interpretation

True negative results, uninformative negatives, known family variants, and follow-up.

NCI + GeneReviews
RET C609Y and C618R report questions

MEN2A context, variant classification, germline testing, sample type, and family follow-up.

NCI + GeneReviews
RET cascade testing for children questions

MEN2 family variants, pediatric timing, targeted testing, counseling, and endocrine follow-up.

NCI + GeneReviews
RET calcitonin follow-up after positive genetic testing

MEN2, medullary thyroid cancer risk, variant-specific planning, and specialist questions.

NCI + GeneReviews
RET family letter questions

MEN2 cascade testing, relatives at risk, variant wording, counseling, and privacy.

NCI + GeneReviews
RET de novo variant questions

MEN2, parent testing, mosaicism, children, family risk, and follow-up.

NCI + GeneReviews
RET VUS family testing questions

Variant uncertainty, MEN2 context, relatives, reclassification, and counseling.

GeneReviews + MedlinePlus
RET mosaicism questions

MEN2, allele fraction, parent testing, sample type, de novo context, and counseling.

GeneReviews + MedlinePlus
RET tumor-only vs germline follow-up

Sample type, MEN2, medullary thyroid cancer, family testing, and counseling questions.

NCI + GeneReviews
RET allele fraction questions

MEN2, mosaicism, tumor-only findings, sample type, germline testing, and family risk.

GeneReviews + NCI
RET paired tumor-normal testing questions

Paired testing, normal comparator samples, tumor-only vs germline interpretation, MEN2, and family follow-up.

NCI + GeneReviews + MedlinePlus
RET normal comparator sample questions

Tumor-normal testing, blood, saliva, MEN2 germline risk, sample limits, and family follow-up.

NCI + GeneReviews
RET saliva vs blood germline testing

MEN2, accepted specimen types, mosaicism, tumor-only follow-up, and family testing questions.

GeneReviews + MedlinePlus
RET result follow-up roadmap

Tumor-only, paired normal, germline, mosaicism, VUS, MEN2 surveillance, and family testing.

NCI + GeneReviews
RET codon and variant comparison guide

M918T, codon 634, V804M, codon groups, VUS results, MEN2 risk, and family testing.

GeneReviews + NCI + MedlinePlus
MEN2 family testing and surveillance roadmap

RET family variants, relatives, children, calcitonin, pheochromocytoma screening, and follow-up.

GeneReviews + NCI + MedlinePlus
Medullary thyroid cancer RET result routing

Germline, tumor-only, VUS, paired tumor-normal, positive germline, and family testing paths.

NCI + GeneReviews + MedlinePlus + ATA
Microbiome testing guide

Gut test evidence, consumer report limits, and claim questions.

FDA + NIH
Stool test vs microbiome test

Medical stool testing, consumer gut reports, diagnosis, sample limits, and symptom red flags.

FDA + NIH
Food sensitivity tests vs allergy tests

IgG panels, IgE testing, skin prick tests, oral food challenges, and why broad panels can mislead.

AAAAI + NIAID
Gut diversity score

Microbiome diversity metrics, stool sample limits, reference databases, and score interpretation.

NIH + FDA
Probiotics and test-based recommendations

Strain-specific evidence, supplement quality, microbiome report claims, and safety questions.

NCCIH + NIH
Postbiotic testing claims

Postbiotic definitions, microbiome report recommendations, supplement claims, and evidence limits.

NCCIH + ISAPP
Microbiome retesting intervals

When repeating gut tests helps, antibiotics and diet changes, sample variability, and score-watching limits.

NIH + FDA
Microbiome test privacy

Sample storage, microbial data, research sharing, HIPAA limits, deletion, and account-security questions.

FDA + FTC + HHS
Vaginal microbiome testing

BV, yeast, STI panels, symptoms, pregnancy questions, and consumer report limits.

CDC + FDA
Microbiome testing after antibiotics

Gut recovery, retesting timing, diarrhea red flags, probiotics, and report limits.

CDC + NIH + NCCIH
SIBO breath test interpretation

Hydrogen, methane, prep, IBS overlap, false positives, and when breath testing helps.

ACG + AGA
Leaky gut and intestinal permeability tests

Zonulin, lactulose-mannitol tests, stool panels, evidence limits, red flags, and claim questions.

NIDDK + AAAAI + PMC
Digestive enzyme testing claims

Stool elastase, lipase, amylase, EPI, supplement marketing, symptoms, and follow-up questions.

NIDDK + AGA
Fecal calprotectin test

IBD, IBS, stool inflammation, infections, NSAIDs, colonoscopy questions, and GI follow-up.

MedlinePlus + NIDDK + Genetics
Fecal calprotectin vs lactoferrin

Stool inflammation markers, IBD vs IBS workups, false positives, and colonoscopy context.

MedlinePlus + PubMed
Stool WBC test and inflammatory diarrhea

Fecal leukocytes, bloody diarrhea, stool culture context, calprotectin comparison, and red flags.

MedlinePlus + CDC
H. pylori testing

Breath tests, stool antigen, blood antibody limits, endoscopy biopsy, prep, and test-of-cure.

MedlinePlus + NIDDK + ACG
Celiac disease blood tests

tTG-IgA, total IgA, gluten intake, biopsy confirmation, HLA testing, and false-negative risk.

MedlinePlus + NIDDK + ACG
GI pathogen panel stool test

Multiplex PCR, infectious diarrhea, stool culture, ova and parasites, C. diff, and result limits.

FDA + IDSA
Lactose intolerance breath test

Hydrogen breath testing, blood glucose follow-up, prep, symptoms, and false positives.

MedlinePlus + NIDDK + Genetics
Pancreatic elastase stool test

Exocrine pancreatic insufficiency, low elastase, stool collection, watery samples, and enzyme questions.

MedlinePlus + AGA
Bile acid malabsorption testing

Chronic watery diarrhea, bile acid diarrhea, serum C4, fecal bile acids, SeHCAT, and treatment trials.

NIDDK + PMC
Fructose breath test

Hydrogen breath testing, fructose malabsorption, IBS overlap, SIBO confusion, prep, and limits.

NIDDK + PMC
Fecal occult blood and FIT tests

Hidden blood in stool, colorectal cancer screening, gFOBT, FIT, FIT-DNA, repeat screening, and colonoscopy follow-up.

CDC + MedlinePlus + USPSTF
Stool ova and parasite test

O&P exams, parasite eggs, travel diarrhea, multiple stool samples, Giardia, exposure history, and limits.

MedlinePlus
Giardia antigen test

Giardiasis stool testing, antigen detection, diarrhea after exposure, O&P comparison, and repeat samples.

CDC + MedlinePlus
Cryptosporidium stool test

Crypto PCR, antigen testing, microscopy, water exposure, repeat samples, and O&P limits.

CDC + MedlinePlus
Cyclospora stool test

Foodborne diarrhea, PCR, modified acid-fast stain, specific lab requests, and public-health context.

CDC
Enteric parasite PCR panels

Stool PCR targets, Giardia, Crypto, Cyclospora, O&P comparison, repeat samples, and panel limits.

CDC + MedlinePlus
Norovirus stool test

RT-qPCR, whole stool, outbreak testing, antigen limits, timing, and clinical decision value.

CDC
Adenovirus stool test

Enteric adenovirus types 40/41, whole stool specimens, PCR, GI panels, outbreak context, and gastroenteritis interpretation.

CDC
Rotavirus stool test

RT-PCR, whole stool, vaccination context, antigen limits, dehydration risk, and outbreaks.

CDC
Sapovirus stool test

Calicivirus gastroenteritis, PCR, GI panels, outbreaks, norovirus-negative testing, and co-detections.

CDC
Astrovirus stool test

Viral gastroenteritis, RT-PCR, GI panels, foodborne outbreak confirmation, and result limits.

CDC + PubMed
Campylobacter stool test

Foodborne diarrhea, stool culture and PCR, susceptibility, public-health reporting, and recovery timing.

CDC
Salmonella stool test

Stool culture, GI panels, severe diarrhea, outbreaks, antibiotic questions, and follow-up context.

CDC
Shigella stool test

Culture, PCR panels, antimicrobial resistance, public-health follow-up, and severe diarrhea context.

CDC
Shiga toxin and STEC stool test

E. coli O157, non-O157 STEC, Shiga toxin testing, HUS risk, and treatment cautions.

CDC
Yersinia stool test

Yersinia enterocolitica, culture, PCR panels, CIN agar, pseudoappendicitis, and iron-overload risk.

CDC + NCBI + MedlinePlus
Vibrio stool test

Seafood and saltwater exposure, culture, PCR panels, TCBS agar, V. vulnificus risk, and urgency.

CDC
Entamoeba histolytica stool test

O&P, antigen, PCR, travel diarrhea, species look-alikes, and amoebiasis follow-up.

CDC
Strongyloides antibody vs stool test

Serology, stool larvae, eosinophils, travel exposure, steroids, and hyperinfection risk.

CDC
Pinworm tape test

Morning tape collection, anal itching, kids, household spread, and why stool tests can miss pinworm.

CDC
Hookworm stool test

Ova and parasite testing, eggs in stool, anemia, eosinophils, travel, and soil exposure.

CDC
Ascaris stool test

Roundworm eggs, O&P microscopy, travel, soil exposure, repeat specimens, and parasite follow-up.

CDC
Trichuris stool test

Whipworm eggs, O&P microscopy, diarrhea, anemia, soil exposure, and repeat stool specimens.

CDC
Taenia tapeworm stool test

Tapeworm eggs, proglottids, O&P microscopy, pork and beef exposure, repeat samples, and species limits.

CDC
Schistosoma testing

Stool, urine, antibody testing, freshwater exposure, travel, egg detection, and species context.

CDC + MedlinePlus + WHO
Echinococcus antibody testing

Hydatid disease, cyst imaging, dog and livestock exposure, serology limits, and specialist review.

CDC
Toxocara antibody testing

Visceral larva migrans, ocular toxocariasis, eosinophils, soil exposure, and stool-test limits.

CDC
Chagas disease antibody testing

Trypanosoma cruzi, Latin America exposure, blood donor screening, chronic infection, and confirmation.

CDC
Loa loa blood smear testing

Loiasis, timed daytime blood smears, microfilariae, West and Central Africa exposure, and eosinophils.

CDC
Filaria antibody testing

Filarial worms, loiasis, onchocerciasis, lymphatic filariasis, exposure history, and cross-reactivity.

CDC
Cysticercosis antibody testing

Neurocysticercosis, Taenia solium larvae, EITB, CT/MRI imaging, seizures, and test limits.

CDC
Trypanosoma brucei testing

African sleeping sickness, tsetse exposure, specimen choice, CSF staging, and CDC/WHO help.

CDC
Baylisascaris antibody testing

Raccoon roundworm, serum and CSF testing, eye findings, neural larva migrans, and exposure history.

CDC
Paragonimus antibody testing

Lung fluke, sputum and stool microscopy, eosinophils, raw crab or crayfish exposure, and CDC serology.

CDC
Gnathostoma antibody testing

Gnathostomiasis, migratory swelling, eosinophils, raw fish exposure, neurologic red flags, and test limits.

CDC + PMC
Fasciola antibody testing

Liver fluke, serology, stool eggs, eosinophils, aquatic plants, liver findings, and CDC context.

CDC
Clonorchis and Opisthorchis antibody testing

Liver flukes, raw fish exposure, stool ova, bile duct disease, serology, and cancer-risk context.

CDC + NCBI
Anisakis allergy and antibody testing

Raw fish exposure, endoscopy, IgE questions, eosinophils, allergy workups, and limits.

CDC + PubMed
Angiostrongylus testing

Rat lungworm, eosinophilic meningitis, CSF, PCR, antibody testing, and travel exposure.

CDC + PubMed
Diphyllobothrium tapeworm testing

Broad fish tapeworm, stool ova and parasite exams, eggs, proglottids, B12, and follow-up.

CDC + MedlinePlus
Strongyloides treatment follow-up testing

Stool exams, serology trends, ivermectin context, persistent symptoms, and immunosuppression.

CDC
Hymenolepis nana tapeworm testing

Dwarf tapeworm, stool ova and parasite exams, eggs, reinfection, children, and follow-up.

CDC + MedlinePlus
Enterobius pinworm treatment follow-up testing

Tape tests, reinfection, household treatment, itching, stool limits, and prevention.

CDC
Dientamoeba fragilis stool testing

O&P, PCR, repeat stool samples, symptom fit, and treatment questions.

CDC + MedlinePlus + PMC
Blastocystis stool test interpretation

Stool PCR or O&P results, colonization questions, symptoms, and treatment uncertainty.

CDC + MedlinePlus
Microsporidia stool and PCR testing

Targeted microsporidiosis workup with stool stains, PCR, immune status, extraintestinal disease, and species limits.

CDC + NIH
Cyclospora repeat testing after treatment

Persistent diarrhea, intermittent shedding, repeat stool specimens, PCR, relapse, and public health.

CDC
Cystoisospora stool testing

Cystoisosporiasis, prolonged watery diarrhea, O&P, modified acid-fast stain, PCR, immune risk, and follow-up.

CDC
Giardia treatment follow-up testing

Persistent symptoms, repeat stool antigen or PCR, ova and parasite testing, reinfection, and treatment failure.

CDC
Entamoeba dispar vs histolytica testing

Stool O&P, antigen, PCR, microscopy limits, amebiasis, nonpathogenic look-alikes, and follow-up.

CDC
Stool PCR positive after symptoms resolve

GI panels, shedding, colonization, C. diff context, test-of-cure limits, and follow-up.

IDSA + CDC + MedlinePlus
Stool PCR co-detection interpretation

Multiple pathogens on GI panels, colonization, shedding, clinical correlation, public health, and follow-up.

IDSA + PMC
Stool PCR negative with persistent diarrhea

GI panel limits, organisms not covered, timing, noninfectious causes, repeat testing, and follow-up.

IDSA + CDC
Stool PCR E. coli pathotype interpretation

ETEC, EPEC, EAEC, STEC, EIEC/Shigella, travel diarrhea, co-detection, and follow-up.

CDC + PMC
Post-infectious IBS testing questions

Persistent diarrhea, stool tests, red flags, fecal calprotectin, celiac testing, and follow-up.

NIDDK + CDC + MedlinePlus
Stool PCR C. difficile co-detection interpretation

NAAT, toxin testing, colonization, diarrhea criteria, multiple pathogen results, and follow-up.

CDC + IDSA + MedlinePlus
Stool PCR norovirus positive interpretation

Viral shedding, outbreaks, GI panels, timing, dehydration risk, public health, and follow-up.

CDC + PMC
Stool PCR sapovirus positive interpretation

Viral gastroenteritis, outbreaks, GI panels, shedding, co-detection, dehydration risk, and follow-up.

CDC + EID + PMC
Stool PCR astrovirus positive interpretation

Viral gastroenteritis, GI panels, outbreaks, children, shedding, co-detection, and follow-up.

CDC + EID + PMC
Stool PCR rotavirus positive interpretation

Viral gastroenteritis, vaccination context, GI panels, shedding, dehydration risk, and follow-up.

CDC
Stool PCR adenovirus positive interpretation

Enteric adenovirus, GI panels, co-detection, timing, immune risk, shedding, and follow-up.

CDC + MedlinePlus + NCBI
Stool PCR Campylobacter positive interpretation

Diarrhea, culture-independent tests, reflex culture, susceptibility testing, public health, and follow-up.

CDC
Stool PCR Salmonella positive interpretation

CIDT, reflex culture, susceptibility testing, shedding, public health, and follow-up.

CDC
Stool PCR Shigella positive interpretation

CIDT, reflex culture, EIEC overlap, antibiotic resistance, public health, and follow-up.

CDC
Stool PCR STEC positive interpretation

Shiga toxin, E. coli O157, HUS risk, culture, antibiotics, public health, and follow-up.

CDC
Stool PCR Yersinia positive interpretation

CIDT, culture, Y. enterocolitica, iron-risk context, pseudoappendicitis, and follow-up.

CDC
Stool PCR Vibrio positive interpretation

CIDT, culture confirmation, seafood exposure, vibriosis, V. vulnificus risk, and follow-up.

CDC
Stool PCR Plesiomonas positive interpretation

CIDT, stool culture, travel or water exposure, symptoms, co-detections, and follow-up.

CDC + PMC
Stool PCR Aeromonas positive interpretation

CIDT, stool culture, water exposure, diarrhea severity, co-detections, and follow-up.

CDC + PMC
Stool PCR Entamoeba histolytica positive interpretation

Amebiasis, travel, dysentery, species specificity, liver abscess context, and follow-up.

CDC
Stool PCR Giardia positive interpretation

Giardiasis, antigen testing, O&P, water exposure, symptoms, co-detections, and follow-up.

CDC
Stool PCR Cryptosporidium positive interpretation

Crypto, watery diarrhea, water exposure, immune risk, co-detections, and follow-up.

CDC
Stool PCR Cyclospora positive interpretation

Cyclosporiasis, produce exposure, prolonged diarrhea, travel, public health, and follow-up.

CDC
Stool PCR enterotoxigenic E. coli positive interpretation

ETEC, traveler's diarrhea, watery diarrhea, co-detections, dehydration, and follow-up.

CDC + PMC
Stool PCR parasite panel false negative questions

Giardia, Crypto, Cyclospora, O&P limits, specimen timing, targets, and follow-up.

CDC
Stool PCR enteroaggregative E. coli positive interpretation

EAEC, persistent diarrhea, travel, co-detections, symptom fit, and follow-up.

CDC + ASM
Stool PCR enteropathogenic E. coli positive interpretation

EPEC, diarrhea in children and adults, travel, co-detections, and follow-up.

CDC + ASM
Stool PCR enteroinvasive E. coli/Shigella positive interpretation

EIEC, Shigella, diarrhea, dysentery, co-detections, and follow-up.

CDC + ASM
Stool PCR C. difficile toxin gene positive interpretation

NAAT, toxin testing, colonization, diarrhea symptoms, and follow-up questions.

CDC + IDSA
C. difficile toxin negative but NAAT positive

Colonization, toxin testing, PCR, diarrhea fit, risk factors, and follow-up.

CDC + IDSA
Stool PCR E. coli co-detection questions

EPEC, EAEC, ETEC, EIEC/Shigella, symptoms, travel, and follow-up interpretation.

CDC + ASM
C. difficile repeat testing questions

PCR, toxin tests, recurrence, test-of-cure limits, ongoing diarrhea, and follow-up.

CDC + IDSA
Stool PCR travel diarrhea co-detection questions

ETEC, EAEC, Giardia, viruses, parasites, symptoms, and travel follow-up.

CDC + PMC
Stool PCR antibiotic-associated diarrhea co-detection questions

C. diff, toxin tests, colonization, other pathogens, antibiotic timing, and follow-up.

CDC
Stool PCR post-infectious IBS questions

Persistent diarrhea, negative panels, shedding, red flags, and follow-up testing.

CDC Yellow Book
Stool culture vs PCR panel

Infectious diarrhea testing, GI panels, organism viability, susceptibility testing, public health follow-up, and result limits.

CDC + IDSA
C. diff testing

Stool PCR/NAAT, toxin tests, GDH, antibiotic-associated diarrhea, colonization, repeat testing, and result limits.

CDC + MedlinePlus
Fecal fat test

Stool fat, malabsorption, steatorrhea, 72-hour collection, pancreatic context, and preparation limits.

MedlinePlus + NCBI
Stool pH and reducing substances test

Carbohydrate malabsorption clues, infant diarrhea context, false results, and adult wellness limits.

MedlinePlus + PubMed
Stool electrolytes and osmotic gap

Chronic watery diarrhea, osmotic vs secretory patterns, stool sodium, potassium, and limits.

PubMed + PMC

Emerging biometrics

Emerging biomarkers guide

How to judge optimization tests, surrogate claims, and wearable metrics.

FDA
CGM for non-diabetics

Continuous glucose monitors, wellness claims, meal spikes, standard testing, and FDA smartwatch cautions.

NIDDK + CDC + MedlinePlus + FDA
Hormone panel tests

Cortisol, testosterone, thyroid, sex hormones, timing, symptoms, and consumer panel limits.

MedlinePlus + FDA
Biological age tests

Epigenetic clocks, blood-based scores, longevity claims, repeatability, and clinical action limits.

PubMed + PMC + NCBI + FDA
Sleep tracking accuracy

Wearable sleep stages, HRV, recovery scores, actigraphy, and when symptoms need evaluation.

NIH + AASM
Wearable heart rate variability

HRV trends, recovery scores, autonomic context, device differences, and symptom red flags.

NIH
VO2 max and fitness estimates

Wearable cardio fitness scores, lab VO2 max, validation limits, and when to trust the trend.

NIH + PMC
Blood pressure wearables

Cuffless estimates, FDA status, home-monitoring technique, validation, and decision limits.

FDA + AHA
Heart rhythm alerts and ECG wearables

AFib alerts, single-lead ECGs, false positives, symptoms, and follow-up testing.

FDA + AHA
Wearable oxygen saturation and respiratory rate

Pulse ox limits, skin tone, motion, low SpO2 alerts, sleep metrics, and symptoms.

FDA + CDC
Skin temperature illness wearables

Fever confusion, cycle tracking, illness-prediction claims, sensor limits, and thermometer use.

CDC + MedlinePlus
Wearable stress scores

HRV, heart rate, EDA, respiratory rate, cortisol confusion, trend use, anxiety, and limits.

NIH + PMC
Recovery and readiness wearables

HRV, sleep scores, resting heart rate, training load, algorithm limits, and when not to follow the score.

AASM + NIH + MedlinePlus
Continuous blood pressure monitoring claims

Cuffless wearables, validation, home cuffs, ambulatory monitoring, FDA status, and limits.

FDA + AHA + NHLBI
Wearable hydration and sweat testing

Sweat sodium, electrolytes, sweat rate, dehydration alerts, athlete use, and accuracy limits.

PMC + MedlinePlus
Body composition scale accuracy

BIA body fat estimates, hydration effects, DXA comparisons, trend use, and decision limits.

MedlinePlus + NIDDK + FDA
Lactate threshold wearable estimates

Running watch algorithms, heart-rate straps, pace, VO2 max links, lab testing, and validation.

PMC
Metabolic cart test

Indirect calorimetry, resting metabolic rate, VO2, CO2, RER, VO2 max, prep, and protocol limits.

PMC
Wearable glucose monitoring claims

Smartwatch and ring claims, CGM displays, FDA warnings, diabetes safety, and validation questions.

FDA + CDC + NIDDK
Continuous ketone monitoring claims

Beta-hydroxybutyrate sensors, DKA safety, validation, lag, and early evidence limits.

CDC + MedlinePlus + FDA
Consumer inflammation score tests

CRP, hs-CRP, ESR, cytokine panels, wellness scoring, nonspecific results, and DTC claim checks.

MedlinePlus + FDA
At-home cortisol rhythm tests

Saliva panels, stress claims, late-night cortisol, Cushing screening, adrenal claims, and consumer-test limits.

MedlinePlus + FDA
NAD testing claims

Blood NAD+, NR, NMN, longevity marketing, supplement claims, assay limits, and human evidence gaps.

NIH + PMC
Consumer metabolomics testing claims

Blood and urine metabolite panels, wellness scores, nutrition recommendations, precision health, validation, and limits.

FDA + PMC
At-home thyroid optimization panels

TSH-first thyroid testing, reverse T3 limits, biotin interference, and optimization claim checks.

MedlinePlus + NIDDK + ATA + FDA + T3
At-home testosterone optimization claims

Low T testing, morning repeat blood tests, saliva and finger-prick kits, symptoms, and treatment risk.

AUA + Endocrine Society
Consumer amino acid panel claims

Plasma amino acids, nutrition dashboards, metabolic-disorder context, supplements, and actionability limits.

MedlinePlus + FDA
At-home menopause hormone panel claims

FSH, estradiol, saliva and urine tests, perimenopause, symptoms, and hormone-therapy claims.

FDA + ACOG
Consumer micronutrient panel claims

Vitamin and mineral blood tests, deficiency risk, supplement recommendations, and wellness-score limits.

FDA + NIH ODS
Consumer heavy metal panel claims

Blood and urine heavy metal testing, lead exposure, mercury and arsenic panels, chelation claims, and actionability.

CDC + FDA
Hair mineral analysis claims

Hair testing for minerals and toxic metals, contamination, lab variability, wellness claims, and better-confirmed tests.

ATSDR + FDA
Mold mycotoxin urine test claims

Urine mycotoxin panels, indoor mold, CDC cautions, FDA DTC-test limits, and detox claims.

CDC + FDA
Food toxin and contaminant panel claims

Food contaminants, metals, mycotoxins, PFAS, FDA monitoring, and broad toxin-score limits.

FDA + CDC + EPA
PFAS blood testing claims

Forever chemicals, blood exposure testing, ATSDR cautions, biomonitoring context, and limits.

ATSDR + CDC
Consumer pesticide exposure panel claims

Urine metabolites, biomonitoring, diet and occupational context, DTC limits, and urgent exposure questions.

CDC + FDA
Phthalate and BPA urine testing claims

Urine metabolites, recent exposure, CDC biomonitoring, source reduction, and DTC limits.

CDC + FDA
Consumer oxidative stress panel claims

Free radicals, antioxidant markers, biomarker validity, wellness scores, supplements, and actionability.

NIH + FDA
Consumer glycation and AGE testing claims

Skin autofluorescence, advanced glycation end products, A1C context, diabetes risk, and actionability.

FDA + PubMed
Consumer mitochondrial function test claims

Lactate, pyruvate, organic acids, fatigue claims, inherited disorders, and wellness-panel limits.

NIH + FDA
Consumer telomere length testing claims

Biological-aging claims, leukocyte telomere limits, lifestyle marketing, and clinical actionability.

NIH + FDA
Consumer exosome biomarker testing claims

Extracellular vesicles, cancer-screening claims, liquid biopsy context, FDA cautions, and evidence gaps.

FDA + NCI
Consumer methylation panel claims

MTHFR, epigenetic clocks, supplement recommendations, detox claims, and clinical utility limits.

FDA + MedlinePlus
Consumer proteomics testing claims

Blood protein panels, disease-risk scores, organ-age claims, cancer biomarker context, and validation.

NIH + FDA
Consumer lipidomics testing claims

Blood lipid species, risk scores, standard lipid panels, ApoB comparison, and clinical validation.

NIH + FDA
Consumer organ-age testing claims

Blood protein organ clocks, kidney/heart/liver age scores, biological age, and actionability limits.

NIH + FDA
Multi-cancer early detection blood test claims

MCED tests, cancer signals, false positives, false negatives, FDA status, and screening limits.

NCI + FDA
Consumer Alzheimer's blood biomarker test claims

p-tau217, amyloid ratios, symptomatic use, screening limits, and clinical follow-up.

FDA + NIH + NIA
Consumer cancer methylation blood test claims

cfDNA methylation, MCED screening limits, positive follow-up, and why standard screening still matters.

NCI + FDA
Consumer insulin resistance score claims

HOMA-IR, LP-IR, fasting insulin, and why A1C or OGTT still drive diagnosis.

NIDDK + CDC + USPSTF
Consumer cortisol stress score claims

Saliva cortisol rhythms, adrenal fatigue claims, stress scores, blood and urine testing, and endocrine follow-up.

Endocrine Society + FDA
Consumer metabolic age score claims

BIA scales, resting metabolic rate, body composition estimates, reference populations, and actionability limits.

NIDDK + FDA
Consumer biological resilience score claims

Aging biomarkers, recovery claims, stress response, biological age, blood proteins, and validation limits.

NIH + FDA
Consumer immune age score claims

Inflammaging, blood proteins, immune cells, biological age, immune resilience, and validation limits.

NIH + FDA
Consumer healthspan score claims

Biomarkers, biological age, fitness, wearables, validation, actionability, and wellness-claim limits.

NIH + FDA
Consumer longevity supplement panel claims

NAD, methylation, nutrients, inflammation, supplement recommendations, and evidence limits.

NIH + FDA
Consumer frailty score claims

Grip strength, gait speed, wearables, biomarkers, aging risk, function, and validation limits.

NIH + FDA
Consumer recovery supplement stack claims

Readiness scores, HRV, inflammation, creatine, protein, electrolytes, supplement safety, and evidence.

NIH + FDA
Consumer overtraining score claims

HRV, cortisol, CK, sleep, performance, inflammation, recovery metrics, and evidence limits.

NIH + MedlinePlus
Consumer sleep debt score claims

Wearables, sleep duration, circadian timing, recovery, sleep quality, and validation limits.

NHLBI + MedlinePlus + CDC
Consumer circadian rhythm score claims

Wearables, sleep timing, light exposure, chronotype, temperature rhythms, and validation limits.

NHLBI + PubMed
Consumer nervous system balance score claims

HRV, sympathetic and parasympathetic signals, stress scores, recovery, symptoms, and caveats.

NCBI + PubMed
Consumer jet lag score claims

Wearables, time zones, circadian timing, sleep debt, light exposure, and travel recovery limits.

CDC + NHLBI
Consumer vagal tone score claims

HRV, parasympathetic activity, breathing, recovery, dysautonomia caveats, and validation limits.

NCBI + PMC
Consumer breathwork score claims

HRV biofeedback, respiratory rate, coherence breathing, stress claims, wearable limits, and validation.

PMC + PubMed
Consumer recovery age score claims

Wearables, readiness, HRV, sleep, biological-age language, recovery trends, and validation limits.

FDA + NIH + MedlinePlus
Consumer meditation score claims

HRV, mindfulness apps, stress, focus, EEG headbands, and validation limits.

NCCIH + FDA
Consumer cognitive readiness score claims

Sleep, HRV, reaction time, focus, fatigue, wearables, and validation limits.

FDA + NHLBI
Consumer focus score claims

Attention apps, sleep, HRV, reaction time, caffeine, wearables, and validation limits.

FDA + NHLBI + MedlinePlus
Consumer caffeine metabolism score claims

CYP1A2, ADORA2A, sleep, anxiety, blood pressure, and genetic testing limits.

NIH + MedlinePlus
Consumer nootropic panel claims

Brain supplements, nutrient tests, genetics, focus scores, FDA label claims, and evidence limits.

FDA + NCCIH
Consumer hydration readiness score claims

Wearables, sweat, urine, electrolytes, dehydration, sodium, and validation limits.

MedlinePlus + FDA
Consumer respiratory fitness score claims

Wearables, respiratory rate, oxygen saturation, VO2 max estimates, exercise capacity, and validation limits.

FDA + NIH
Consumer autonomic age score claims

HRV, autonomic balance, wearable age scores, recovery claims, and clinical caveats.

FDA + NIH
Consumer recovery debt score claims

Wearables, HRV, sleep debt, training load, readiness, fatigue, and validation limits.

FDA + PMC + MedlinePlus
Consumer training age score claims

Fitness age, VO2 max estimates, training load, age-like labels, and validation limits.

FDA + PMC
Consumer strain score claims

Wearables, HRV, training load, stress, recovery, and validation limits.

FDA + PMC
Consumer load management score claims

Training load, recovery, wearable advice, injury-risk language, and validation limits.

FDA + PMC
Consumer exertion tolerance score claims

Wearables, VO2 max estimates, heart rate, fatigue, recovery, symptoms, and validation limits.

FDA + PMC
Consumer illness risk score claims

Temperature, HRV, respiratory rate, sleep, symptom prompts, clinical testing caveats, and validation limits.

FDA + PMC
Consumer heat strain score claims

Wearables, heat stress, heart rate, skin temperature, hydration, work-rest decisions, and validation limits.

CDC + PMC
Consumer recovery reserve score claims

Wearables, HRV, sleep, training load, readiness, fatigue, and validation limits.

FDA + PMC
Consumer dehydration risk score claims

Wearables, sweat, urine, electrolytes, heat exposure, symptoms, and validation limits.

MedlinePlus + FDA
Consumer altitude readiness score claims

Wearables, SpO2, HRV, ascent rate, acclimatization, altitude illness, and validation limits.

CDC + FDA
Consumer sweat electrolyte score claims

Wearables, sweat sodium, hydration planning, sports use, overhydration, validation, and limits.

MedlinePlus + CDC
Consumer respiratory load score claims

Wearables, respiratory rate, oxygen saturation, illness detection, training load, altitude, and validation limits.

FDA + CDC
Consumer oxygen debt score claims

Wearables, exercise recovery, VO2, CPET, lactate, oxygen deficit language, validation, and limits.

NCBI + FDA + MedlinePlus
Consumer ventilation efficiency score claims

Wearables, VE/VCO2, CPET, breathing patterns, oxygen saturation, exercise testing, and validation limits.

PMC + FDA
Consumer breathing reserve score claims

Wearables, CPET ventilatory reserve, respiratory rate, oxygen saturation, symptoms, and validation limits.

NCBI + FDA
Consumer CO2 tolerance score claims

Breath holds, capnography, end-tidal CO2, CPET, breathing apps, anxiety and training claims, and validation limits.

NCBI + FDA
Consumer respiratory recovery score claims

Wearables, respiratory rate, oxygen saturation, training recovery, CPET context, symptoms, and validation limits.

NCBI + FDA + MedlinePlus
Consumer breathing age score claims

Wearables, lung age language, respiratory rate, CPET, spirometry context, symptoms, and validation limits.

NCBI + FDA
Consumer oxygen recovery score claims

Wearables, VO2 recovery, CPET, oxygen saturation, training recovery, symptoms, and validation limits.

NCBI + FDA
Consumer respiratory strain score claims

Wearables, breathing load, CPET, oxygen saturation, exercise signals, symptoms, and validation limits.

NCBI + FDA
Consumer breathing efficiency score claims

Wearables, CPET, ventilation, respiratory rate, oxygen saturation, training, and validation limits.

PMC + FDA
Consumer oxygen reserve score claims

Wearables, oxygen saturation, VO2, CPET, altitude, symptoms, and validation limits.

NCBI + FDA
Consumer ventilatory reserve score claims

Wearables, CPET breathing reserve, respiratory rate, oxygen saturation, symptoms, and validation limits.

NCBI + FDA
Consumer respiratory resilience score claims

Wearables, illness recovery, respiratory rate, oxygen saturation, CPET context, and validation limits.

NCBI + FDA
Consumer respiratory capacity score claims

Wearables, CPET, lung function language, VO2, respiratory rate, oxygen saturation, and validation limits.

NCBI + FDA
Consumer oxygen capacity score claims

Wearables, VO2 max, CPET, oxygen saturation, altitude, anemia, and validation limits.

NCBI + FDA
Consumer oxygen utilization score claims

Wearables, VO2, CPET, SpO2, recovery, altitude, training, and validation limits.

NCBI + FDA
Consumer breathing capacity score claims

Spirometry, CPET, respiratory rate, oxygen saturation, wearables, symptoms, and validation limits.

NCBI + FDA
Consumer respiratory efficiency score claims

CPET, breathing rate, SpO2, VO2, wearables, ventilation, and validation limits.

NCBI + FDA
Consumer oxygen efficiency score claims

Wearables, VO2, CPET, pulse oximetry, recovery, and validation limits.

NCBI + MedlinePlus + FDA
Consumer respiratory reserve score claims

CPET, breathing reserve, SpO2, respiratory rate, wearables, symptoms, and validation limits.

NCBI + FDA
Consumer oxygen load score claims

Wearables, VO2, SpO2, exercise load, altitude, recovery, symptoms, and validation limits.

NCBI + FDA + MedlinePlus
Consumer respiratory recovery load score claims

Wearables, breathing, SpO2, CPET concepts, recovery trends, and validation limits.

NCBI + FDA
Consumer oxygen strain score claims

Wearables, SpO2, VO2 estimates, CPET concepts, altitude, symptoms, and safety limits.

NCBI + FDA
Consumer breathing strain score claims

Wearables, respiratory rate, SpO2, CPET concepts, symptoms, and validation limits.

NCBI + FDA
Consumer oxygen recovery load score claims

SpO2, VO2 estimates, wearables, CPET concepts, altitude, symptoms, and limits.

NCBI + FDA
Consumer respiratory recovery burden score claims

Wearables, breathing rate, SpO2, CPET concepts, symptoms, and validation limits.

NCBI + FDA
Consumer oxygen readiness score claims

SpO2, VO2 estimates, wearables, recovery, CPET concepts, symptoms, and limits.

NCBI + FDA
Consumer breathing readiness score claims

Respiratory rate, SpO2, CPET concepts, wearables, symptoms, and validation limits.

NCBI + FDA
Consumer oxygen adaptation score claims

Altitude, SpO2, VO2 estimates, wearables, training adaptation, and limits.

NCBI + FDA
Omega-3 index test

EPA, DHA, red blood cell fatty acids, supplement caveats, and evidence limits.

NIH + NCCIH